Search results for "food simulants"

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Determination of 60 Migrant Substances in Plastic Food Contact Materials by Vortex-Assisted Liquid-Liquid Extraction and GC-Q-Orbitrap HRMS

2021

A GC-HRMS analytical method for the determination of 60 migrant substances, including aldehydes, ketones, phthalates and other plasticizers, phenol derivatives, acrylates, and methacrylates, in plastic food contact materials (FCM) has been developed and validated. The proposed method includes migration tests, according to Commission Regulation (EU) 10/2011, using four food simulants (A, B, C, and D1), followed by vortex-assisted liquid–liquid extraction (VA-LLE) and GC-Q-Orbitrap HRMS analysis in selected ion monitoring (SIM) mode, with a resolving power of 30,000 FWHM and a mass accuracy ≤5 ppm. The method was validated, showing satisfactory linearity (R2 ≥ 0.98 from 40 to 400 …

gas chromatographyLiquid-Liquid ExtractionOrganic ChemistryFood PackagingPharmaceutical ScienceFood Contaminationfood contact materialsArticleMass Spectrometrymigration testAnalytical ChemistryQD241-441food simulantsPlasticizersChemistry (miscellaneous)Drug DiscoveryMolecular Medicinehigh-resolution mass spectrometrytarget analysisPhysical and Theoretical ChemistryPlasticsfood contact materials; food simulants; gas chromatography; high-resolution mass spectrometry; migration test; target analysisMolecules; Volume 26; Issue 24; Pages: 7640
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